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What are the different categories of exotoxins, and how do they function?

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The three categories are AB toxins, cyto...

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Which of the following is NOT an example of an AB toxin?


A) shiga-like toxin
B) hemolysins
C) botulinum toxin
D) tetanus toxin

E) B) and C)
F) None of the above

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________ in saliva cleaves glycosidic linkages in the peptidoglycan that is present in bacterial cell walls, weakening the wall and potentially causing cell lysis.


A) Mucus
B) Lysozyme
C) Fibrin
D) Lipid A

E) A) and B)
F) A) and C)

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B

R plasmids help prevent the spread of virulence factors.

A) True
B) False

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________ is a damage or injury to a host organism that impairs its function.


A) Trauma
B) Infection
C) Disease
D) Transmission

E) B) and C)
F) All of the above

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Escherichia coli is commonly found in the normal human microbiota, but some strains can cause severe illness. What is the difference between pathogenic and non-pathogenic E. coli in relation to the human host?

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Most nonpathogenic E. coli strains are f...

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________ are toxic proteins released from the pathogen during normal growth.


A) Endotoxins
B) Exotoxins
C) Macrotoxins
D) Microtoxins

E) All of the above
F) C) and D)

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Cholera begins following a bite from a mosquito.

A) True
B) False

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The dose of an antigen that kills 50% of animals in a test group and is used to estimate the virulence of a pathogen is known as


A) Antigen dose₅₀.
B) Virulence-50.
C) LD₅₀ (lethal dose₅₀) .
D) Death rate-50.

E) B) and C)
F) C) and D)

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Which of the following is a major growth-limiting micronutrient that influences microbial growth?


A) iron
B) water
C) vitamin K
D) sugar

E) B) and C)
F) B) and D)

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Virulence genes may be located on mobile genetic elements.

A) True
B) False

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TRUE

Explain how diet plays a role in the development of dental caries.

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Sugar in the human diet contributes to d...

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Pathogen virulence NEVER changes throughout a hostʹs life.

A) True
B) False

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The condition that results when some bacteria are shed in the bloodstream and distributed to distant parts of the body but do not reproduce in the blood is called


A) septicemia.
B) bacteremia.
C) uremia.
D) erythemia.

E) C) and D)
F) B) and C)

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An endogenous pyrogen is


A) a chemical from the bacterial cell wall that causes fever.
B) a chemical produced by a host's own immune system that causes fever.
C) a chemical released by a bacterial cell that causes fever.
D) a chemical produced within a bacterial cell that is released during cell division or at death of the bacterium, at which point it causes fever.

E) A) and B)
F) None of the above

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Compared with an endotoxin, would a bacterial exotoxin generally be more likely to function after it had been significantly heated?


A) Yes, because exotoxins are very heat stable compared to endotoxins.
B) Yes, because exotoxins are proteins and non-living but endotoxins are part of the bacterial cell wall.
C) No, because exotoxins are carbohydrates and endotoxins are proteins.
D) No, because exotoxins are heat-labile and less resistant to heating than endotoxins.

E) A) and B)
F) A) and C)

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Which of the following pathogens does NOT use capsules or a slime layer for attachment?


A) Vibrio cholera
B) Streptococcus pneumonia
C) Bacillus anthracis
D) All of these pathogens use capsules or slime layers for attachment.

E) A) and D)
F) A) and C)

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A

Pathogenicity and virulence differ in that


A) pathogenicity refers to the overall ability of a microbe to cause disease, whereas virulence refers to the ability of one microbe to cause disease relative to another.
B) virulence refers to the overall ability of a microbe to cause disease, whereas pathogenicity refers to the ability of one microbe to cause disease relative to another.
C) pathogenicity only refers to pathogens, whereas virulence refers to any microbe that can cause an infection.
D) virulence only refers to pathogens, whereas pathogenicity refers to any microbe that can cause an infection.

E) B) and D)
F) B) and C)

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Tetanus toxin causes


A) muscles to be unable to relax.
B) muscles to be unable to contract.
C) severe diarrhea.
D) hemolytic uremic syndrome.

E) A) and B)
F) A) and C)

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Invasion is the ability of a pathogen to enter into host cells or tissues, spread, and cause disease.

A) True
B) False

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